Shabzain Ishrat; Adeel Zafar; Farheen Hameed; Sibgha Bashir; Sara Khan; Rizwan Hafeez
Abstract
Worldwide many people are affected by Type 2 Diabetes mellitus (DM). This study aimed to assess how lipid and glycemic parameters are affected by ascorbic acid in adult population suffering ...
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Worldwide many people are affected by Type 2 Diabetes mellitus (DM). This study aimed to assess how lipid and glycemic parameters are affected by ascorbic acid in adult population suffering from type 2 DM. Two groups were formed one was control group with 103 patients and other was treatment group with 103 patients. The intervention group was administered 500 mg of vitamin C three times a day in conjunction with oral hypoglycemic medications for duration of three months. Fasting blood sugar, random blood sugar, glycosylated hemoglobin, total cholesterol, serum triglycerides, high density lipoproteins cholesterol, and low density lipoproteins cholesterol tests were conducted at start of study and again after three months. Means were compared between control and treatment groups. Correlation and regression analysis between vitamin C and laboratory parameters were also performed. Lipid profile, fasting blood sugar, and random blood sugar were affected significantly by ascorbic acid and there was significant correlation between them. However, regression analysis revealed that, except for high-density lipoprotein cholesterol, there was no statistical significance in the impact on the overall lipid profile. The current study's conclusion suggests that administering vitamin C as supplementary therapy alongside anti-diabetic medications, over an extended period and in divided doses, can influence glycemic parameters and lipids.
